Rosie O’Donnell has delivered a stinging response to President Donald Trump after he shared on his Truth Social platform an AI-generated video portraying himself as a doctor treating his celebrity critics — including O’Donnell — for the fictional “Trump Derangement Syndrome.”

“He’s quite ill – and getting worse daily. The 25th amendment exists for exactly this reason. Remove. Impeach. Convict,” O’Donnell told The Guardian on Thursday.

The Trump-O’Donnell feud has stretched back nearly two decades, with both taking turns in attacking the other.

After Trump won the 2024 election, the actor and former TV host moved to Ireland, saying the decision was made out of concern for her own well-being and self-preservation.

Trump has since suggested stripping O’Donnell of her U.S. citizenship, despite the president having no authority to do so.

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