The US-Israel war on Iran hit century-old medical research centre the Pasteur Institute and a bridge near Tehran.

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The United States and Israel are widening their attacks on Iran, hitting infrastructure in and around the capital, as Washington ramps up pressure on Tehran and the conflict spreads across the region.

Meanwhile, US Defense Secretary Pete Hegseth has abruptly fired the US Army’s top general and two other senior officers, prompting speculation of a wartime leadership shake-up.

Here is what we know: